Digital technologies advancement and their increasing application to prosthetic dentistry pose new challenges and expectations for both clinicians and dental technicians. The traditional fabrication of removable partial and complete dentures, as well as postoperative obturators, is a time-consuming process that is susceptible to human error, which may affect the quality of the final prosthetic restorations. The use of digital technologies makes it possible to shorten and simplify the manufacturing proces of prosthetic restorations, thus providing more predictable outcomes in terms of mechanical strength. Additionally, the digital workflow enables efficient communication between the clinician and the dental technician, as well as between clinicians from different medical centres, while the archiving of designed prosthetic items facilitates their easy reproduction. The use of intraoral scanners may be useful for recording data of the prosthetic foundation in patients whose anatomical conditions exclude conventional impression taking. However, it should be remembered that digital workflows have limitations, particularly in accurately reproducing the edentulous prosthetic foundation. Despite the rapid development of CAD/CAM technology, the fully digital workflow for the fabrication of removable dentures still presents significant clinical limitations. The greatest challenges involve mapping the compliance of the basal seat, registering the boundaries of the, and scanning extensive postoperative defects. In many clinical cases, conventional impressions remain a more predictable diagnostic and therapeutic method.