Introduction:
Anti-cancer therapy includes surgical management, radiotherapy and chemotherapy. Surgery is connected with disruption of tissue continuity, post-surgical defects, healing period and post-operative rehabilitation. The iatrogenic effects of chemotherapy and radiation results in systemic complications and the emergence of lesions in the oral cavity that require adequate dental treatment.

Aim of the study:
To review the literature relating to the effects of anticancer therapy on the condition of the prosthetic foundation area and planned treatment.

Material and methods:
Using the key words: „radiotherapy”, „chemotherapy” and „oral complication”, PUBMED database with articles in English from 1983-2017 was searched, as well as Polish language publications from 2005-2016 using the search words: “oncology” and “oral cavity ”.

Results:
Based on 40 articles, the analysis of the impact of oncological treatment on the condition of the prosthetic base was made. Chemotherapy and irradiation exert adverse reactions in mineralized and soft oral tissues, such as resorption and necrotic changes in the bones, inflammation of the mucosa with associated infections, and caries. The outcome of prosthetic treatment is also affected by disorders in salivary secretion, limited mobility of the temporo-mandibular joint and the reduced activity of masseter muscles.

Conclusions:
Due to the iatrogenic effect of oncological treatment on oral tissues, regular control and correction of the restorations is recommended. Often, post-procedural prosthetic treatment has to be deferred due to unstable anatomical conditions.