REVIEW PAPER
Surface modifications of the transmucosal region of implant-prosthetic
components influencing the response of gingival fibroblasts
– a review of methods
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Katedra i Zakład Protetyki Stomatologicznej, Warszawski Uniwersytet Medyczny
These authors had equal contribution to this work
Submission date: 2025-10-02
Final revision date: 2025-11-24
Acceptance date: 2025-12-02
Publication date: 2025-12-10
Prosthodontics 2025;75(4):339-348
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ABSTRACT
Dental implants enable the reconstruction of dentition in the case of single missing tooth, mixed deficiencies, and in edentulous patients. The long-term success of implantation depends not only on the quality and quantity of the alveolar bone, but also on the integration of the elements of prosthetic reconstruction with the adjacent soft tissues, which has a significant impact on the prevention of peri-implantitis and thus on the long-term survival of the implant. Proper preparation of the surface of the transmucosal element, which is in direct contact with soft tissues, enables its colonization by gingival fibroblasts (GFs). For the fibroblast reaction, the key feature of the biomaterial is the characteristics of its surface, i.e. its topography and its physicochemical properties. This has led researchers to explore various methods for developing the transmucosal surface of the implant e.g. by mechanical processing, photoactivation, the use of cold plasma, laser modification and argon plasma coating, or the use of biological coatings. The work was based on 36 publications available in the PubMED database in English and articles published in polish dental journals in the years 2015-2025, which concerned the survival of implants and methods of modifying the transmucosal part of the implant and their impact on GFs.