In the case of the single missing teeth, the implant-retained prosthetic restoration is a predictable solution, functionally and aesthetically favorable and currently widely used. The position of the long axis of the implant may result from the surgical conditions, but it also affects the method of construction of the prosthetic restoration and its aesthetics. In the clinical observations, screw-retained restorations are considered the most suitable solution. However, until recently, their use was limited by the location of the screw opening, which was located in the extension of the implant axis. If the screw opening was located on the vestibular surface or the incisal edge, it was necessary to make the cement-retained restoration. The modern methodology of making screw-retained restorations using special screws and drivers that allow the screw opening to be redirected to a more favorable location (the palatal surface of the restoration or the middle of the occlusal surface) is described in the paper. Moreover, it is presented how this problem was solved with the own modification for the patient treated 25 years earlier.